Trio sequencing1

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  Genetic and chemotherapeutic influences on germline hypermutation Genetic and chemotherapeutic influences on germline hypermutation | Nature 2022, Nature Raheleh Rahbari & Matthew Hurles groups Here we analysed the genome wide sequences of 21,879 families with rare genetic diseases and identified 12 individuals with a hypermutated genome with between two and seven times more de novo single nucleotide variants than expected. In most families (9 out of 12), the .. 논문 리뷰/Other topics 2022. 5. 16.