MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles - ScienceDirect
MicroRNA profile in the squamous cell carcinoma: prognostic and diagnostic roles
Head and neck squamous cell carcinomas (HNSCCs) are human malignancies associated with both genetic and environmental factors. MicroRNAs (miRNAs) as a…
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MicroRNAs and head and neck cancer: Reviewing the first decade of research - ScienceDirect
MicroRNAs and head and neck cancer: Reviewing the first decade of research
MicroRNAs are a class of non-coding RNA which regulate gene expression. Their discovery in humans in 2000 has led to an explosion in research in this …
www.sciencedirect.com
https://www.pacb.com/blog/ploidy-haplotypes-and-phasing/
Sequencing 101: ploidy, haplotypes, and phasing — how to get more from your sequencing data - PacBio
Phasing involves separating maternally and paternally inherited copies of each chromosome into haplotypes to get a complete picture of genetic variation.
www.pacb.com
Mitochondrial RNA modifications shape metabolic plasticity in metastasis | Nature
Mitochondrial RNA modifications shape metabolic plasticity in metastasis - Nature
a, Metastasis-initiating CD44+CD36+ cells. b,c, Flow cytometry (b) and CMXROS quantification (c) of CD36 and CD44 high (H) and low (L) VDH01 cells (n = 3 sorts). d, NSUN3 RNA in FaDu subpopulations (n = 9; 3 quantitative PCR with reverse transcript
www.nature.com
De novo design of discrete, stable 310-helix peptide assemblies | Nature
The metastatic spread of breast cancer accelerates during sleep | Nature
The microbiome and gut homeostasis (science.org)
APOE told me put my fat in the bag and nobody gets hurt: Cell
Antibiotic discovery with machine learning | Nature Biotechnology
Advancing code sharing in the computational biology community | PLOS Computational Biology
Advancing code sharing in the computational biology community
Citation: Cadwallader L, Mac Gabhann F, Papin J, Pitzer VE (2022) Advancing code sharing in the computational biology community. PLoS Comput Biol 18(6): e1010193. https://doi.org/10.1371/journal.pcbi.1010193 Published: June 2, 2022 Copyright: © 2022 Cadwa
journals.plos.org
Spatial modelling for population replacement of mosquito vectors at continental scale
Author summary Conventional control methods have dramatically reduced malaria, but it still kills over 300,000 children in Africa each year, and this number could increase as their effectiveness wanes. Novel control methods using gene drives rapidly reduce
journals.plos.org
Learning the statistics and landscape of somatic mutation-induced insertions and deletions in antibodies
Author summary Affinity maturation of B cell receptors is an important mechanism by which our body designs neutralizing antibodies to defend us against pathogens, including broadly neutralizing antibodies, which target a wide range of variants of the same
journals.plos.org
Characterizing collaborative transcription regulation with a graph-based deep learning approach
Author summary Human transcription activities are regulated by chromatin features including transcription factor binding, histone modification, and DNase I hypersensitive site. Recently many computational models are proposed to predict chromatin features f
journals.plos.org
Two types of critical cell density for mechanical elimination of abnormal cell clusters from epithelial tissue
Author summary High-resolution imaging techniques have revealed that abnormal cells developing in epithelial tissues are mechanically eliminated via contraction at the interface between the abnormal cells and normal surrounding cells. This phenomenon is se
journals.plos.org
Explainable detection of adverse drug reaction with imbalanced data distribution
Author summary Post-marketing drug safety surveillance offers the chance to detect serious ADRs resulting in hospitalization and ADRs occurring in patients, e.g., patients with high comorbidity and receiving drugs that are administered only in hospitals. T
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Prediction and expression analysis of deleterious nonsynonymous SNPs of Arabidopsis ACD11 gene by combining computational algori
Author summary Non synonymous single nucleotide polymorphism (nsSNP) is a process in which amino acid sequence of a protein is altered as a result of single nucleotide alteration in the coding region (mRNA) of any living organism. Therefore, the entire pro
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Integrated view and comparative analysis of baseline protein expression in mouse and rat tissues
Author summary We have reanalysed 23 baseline mass spectrometry-based public proteomics datasets stored in the PRIDE database. Overall, the aggregated dataset contained 211 samples, coming from 34 different tissues across 14 organs, comprising 9 mouse and
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